Scientists around the world utilize human cell cultures or derived DNA as the primary resource for multidisciplinary investigations. These studies allow major scientific breakthroughs which constitutes the basis for early diagnosis, prevention, and/or new medical treatments of diseases. From four teaspoonfuls of blood or a skin biopsy, it’s possible to establish cell cultures which can be used by scientists worldwide to study genetic and rare diseases.

BioRep S.r.l. (www.biorep.it) is an independent “SERVICE PROVIDER” organization born in 2003 by the conjunctive investment of Sapio Life, Angelantoni Industries and Integrated Systems Engineering, offering biorepository services to public and private research institutes, to the highest standards of quality and safety. A cell repository, or cell bank, is a collection of living cells maintained indefinitely at extremely low temperatures in a state of suspended animation. BioRep is a technologically advanced infrastructure able to provide several services to meet the needs of the entire Scientific Community.

The company’s objective is to become the leading biorepository service provider in Europe, with the aim of contributing to the advancement of medical research and scientific discovery, bringing today’s state-of-art technology and science to its portfolio of biorepository services and capabilities.

Thanks to an exclusive agreement with Coriell Institute for Medical Research, the oldest and largest biorepository of the world, BioRep is specialized in cell lines preparation, in nucleic acid extraction and long term storage in liquid nitrogen (-196° C) and in refrigerators -80°C of any kind of biosamples, using procedures and standards developed by Coriell in over 50 years of activity.

BioRep and Coriell together constitute one of the few “Global Biorepository” able to serve the pharmaceutical industries for world wide clinical trials. BioRep facility is specifically designed to give the utmost efficiency and security by implementing Coriell procedures and standards.

In addition to the storage service, BioRep provides Cell Biology, Molecular Biology, Microbiology, Media preparation services developed in ISO9001/2000 certified laboratories. The modern bank infrastructure for the storage of the biological material in liquid Nitrogen is supported by monitor and control system, based on PLC (Programmable Logic Controller) Technology, able to register and certify all the operative parameters of critical machines (incubators, laminar flux hood, cold rooms…etc), and to activate a very sophisticated alarm system (24 h/day for 365 days/year) in case of emergency. BioRep is committed to a flexible and innovative approach for all of its contract services to assure the particular needs of the individuals requesting the services.

The clinical trials for drug validation are now performed globally; many disease screening studies are being carried by associated research group using an enormous number of patients. In addition, the rapid progress on stem cell research will soon require the realization of facilities to properly preserve these cells for transplantation. For these reasons, there will be strong demands to store large quantities of biomaterials in safe biorepositories by the entire scientific community, and BioRep will become one of the reference centre in Europe able to satisfy these needs.