Cryopreservation Equipment Supply
BioRep is an authorized distributor, and for selected product lines the exclusive distributor, of Chart-MVE and Brooks Automation steel and aluminum cryogenic storage systems.
BioRep provides high-quality solutions for cold storage management, supplying state-of-the-art equipment designed to ensure the safety, integrity, and quality of cryopreserved biological samples.
Biological Sample Storage Solutions
BioRep offers one of the most comprehensive ranges of Chart-MVE products for both short- and long-term storage in liquid nitrogen and nitrogen vapor.
These storage systems undergo the most stringent quality control procedures and deliver:
- Outstanding vacuum performance
- High operational reliability
- Exceptional durability and longevity
Chart-MVE certifications include:
- CE
- MDD
- UL
- IATA
- TGA
- ISO 9001
Automatic-Fill Stainless Steel Cryogenic Storage Systems
High-performance Chart-MVE stainless steel cryogenic storage systems are equipped with dedicated controllers for:
- Temperature monitoring
- Liquid nitrogen level monitoring
- Automatic liquid nitrogen refilling
The systems are also equipped with visual and audible alarms and can be fully integrated with centralized monitoring and control platforms.
Designed specifically for storage in nitrogen vapor or liquid nitrogen immersion, these systems can accommodate large quantities of biological materials, ranging from 5,000 to 90,000 samples stored in 2 mL vials, as well as blood bags and cryogenic straws. Storage chambers can be configured with either standard or customized internal layouts.
Selected models also allow users to regulate and customize internal operating temperatures directly through the control unit across a range from -20°C to -150°C.
Manual-Fill Aluminum Containers
Chart-MVE aluminum cryobiological containers are designed for storing small to medium quantities of biological samples, straws, and vials, with a capacity of up to 6,000 units, while ensuring good holding times and low liquid nitrogen consumption.
Lightweight and easy to handle thanks to their aluminum construction and wheeled base, these containers are particularly well suited to the needs of assisted reproduction centers and small research biobanks.
Products for the Transport of Biological Samples
Steel or aluminum cryogenic containers designed for transporting cryopreserved biological samples in nitrogen vapor (vapor shippers), equipped with temperature data loggers to monitor conditions during transport and compliant with ADR and IATA regulations.
Inside, a hydrophobic membrane absorbs liquid nitrogen and releases it as vapor, maintaining an internal temperature of -150°C.
Depending on the model and intended use, holding time can reach up to 20 days, with a 3-hour recharge time for long-distance transport, or up to 4 hours, with a 10-minute charging time for intra-hospital or emergency transfers.
Products for the Storage and Transport of Liquid Nitrogen
Cryogenic tanks are specifically designed for the transport and storage of liquid nitrogen only. They are used to refill manual cryobiological containers or can be connected directly to automated equipment.
Some models are self-pressurizing and are generally made of steel. They can store large volumes of liquid nitrogen, ranging from 30 to 600 liters, and can be easily moved thanks to wheels welded directly to the body of the container.
Other models are made of aluminum and are designed for the storage and transport of smaller quantities of liquid nitrogen, from 4 to 50 liters. They are lightweight and easy to handle, either by lifting or with the use of a dedicated wheeled base.
The primary goal of cryopreservation is to maximize cell viability during both freezing and thawing processes.
To achieve controlled and gradual freezing, it is essential to accurately regulate cooling rates until the desired temperature is reached. Controlled-rate freezing is performed using specialized freezers that cool samples through the introduction of nitrogen vapor into the freezing chamber.
BioRep is the official distributor and service provider for PLANER Plc controlled-rate freezers, recognized worldwide as one of the leading technologies for biological sample cryopreservation.
These systems are specifically designed for the freezing of:
- Blood-derived products
- Biological tissues
- Cellular therapies
- Other biological materials stored in bags, vials, and cryogenic straws
Key advantages include:
- Compact design
- Top-loading configuration
- Optimized cooling distribution through laminar airflow technology
- Flexible time and temperature control
- High-volume processing capabilities
The superior insulation of the freezing chamber enables temperature control with precision down to one hundredth of a degree, allowing highly customized freezing protocols.
All PLANER systems are certified in accordance with European Medical Device Directive 93/42/EEC requirements.
Cryosurgery utilizes extremely low temperatures to destroy abnormal or diseased tissues.
In dermatology, cryosurgery is widely used because it:
- Typically does not require anesthesia
- Is minimally painful
- Rarely causes scarring
- Requires limited post-treatment care
- Offers minimal recovery time
The most common application is the treatment of warts, although cryosurgery is also used for:
- Actinic keratoses
- Lentigo simplex
- Condyloma acuminata
- Molluscum contagiosum
- Skin tags
- Nevi
- Basal cell carcinoma
BioRep supplies a range of stainless steel pressurized cryosurgical systems characterized by exceptional durability and low static evaporation rates.
These devices allow liquid nitrogen to be accurately directed onto the treatment area through spray tips of varying diameters.
Equipment is supplied with dedicated tabletop supports to ensure safe and convenient usage.
The systems can be refilled using Chart-MVE aluminum cryogenic containers ranging from 4 to 50 liters, either through direct transfer or pressurized dispensing systems.
Working with liquid nitrogen requires a thorough understanding of the associated safety risks.
In addition to oxygen displacement resulting from nitrogen evaporation, which may lead to asphyxiation hazards, liquid nitrogen’s extremely low temperature can cause severe cold burns through direct contact with either the liquid itself or cryogenic surfaces.
To protect personnel from these risks, BioRep supplies a complete range of certified personal protective equipment for liquid nitrogen applications, including:
- Waterproof cryogenic gloves available in multiple sizes
- Protective face shields featuring lift-up transparent visors and adjustable headgear
- Cryogenic aprons with adjustable neck and waist fastening systems, available in multiple sizes
- Cryogenic over-shoe gaiters
BioRep also offers PASS COLT and SAFER CF15 self-contained breathing apparatus systems complete with external emergency safety cabinets for use when cryobiology rooms become inaccessible and emergency response is required.
A complete range of cryogenic safety signage is available for installation inside and around cryogenic facilities.
All PPE supplied by BioRep complies with applicable international safety standards and regulations.