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Cellular Biology

The BioRep Cell Repository establishes, maintains and distributes cell line cultures as well as DNA derived from these cultures. The scientific and business affiliation between BioRep and the Coriell allows to have access to more than a million types of cell vials, stored in liquid nitrogen. Cells, that have been stored for nearly 50 years, are still viable and available for research purposes today.

This is made possible by the highly standardized techniques developed and applied by the Coriell staff. BioRep only recently began to create its own cell library, but the combined contents of the Coriell-BioRep cryogenic repository is the largest collection in the world.


BioRep provides the following services:

Establishment of cell lines

  • Epstein-Barr Virus (EBV) transformed lymphoblast cultures from human blood;
  • Fibroblasts, endothelial, smooth muscle and epithelial cell cultures from appropriate tissue biopsies.


Cell banking of public and private collections

  • Cryopreservation of primary or transformed cell lines;
  • Cryopreservation of peripheral blood mononuclear cells (buffy coats), and plasma;
  • Maintenance of seed and distribution stocks;
  • Expansion of cell lines for molecular and cytogenetic Analysis;
  • Embryonic, foetal and adult stem cells culturing;
  • Tumor cell culturing;
  • Viability and sterility controls on customer cell lines;
  • Differentiation tests on stem cell.